Contact Us
University of Kentucky, PSS 
KTRDC1401 University Drive (Office:123)
Lexington, KY 40546-0236
(859) 257-4806
(859) 323-1077
Publications
2012
- Jordan, D.B., Wagschal, K., Fan, ZM, Yuan, L., Braker, J.D. and Heng, C. 2011. Engineering lower inhibitor affinities in beta-D-xylosidase of Selenomonas ruminantium by site-directed mutagenesis of Trp145. Journal of Industrial Microbiology and Biotechnology. (in press)
- Suttipanta, N., Pattanaik, S., Kulshrestha, M., Patra, B., Singh, S.K. and Ling Yuan, 2011. The Transcription Factor CrWRKY1 Positively Regulates Terpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus. Plant Physiology. (in press) doi: 101104/pp.111.181834
- Fan, ZM and Ling Yuan. 2010. Production of Multifunctional Chimeric Enzymes in Plants: a promising Approach for Degrading Plant Cell Wall from Within. Plant Biotechnology Journal. 8:308-315
- Fan, ZM., Yuan, L., Jordan, DB., Wagschal, K., Heng, C., Braker, JD. 2010. Engineering Lower Inhibitor Affinities in Beta-D-xylosidase. Applied Microbiology and Biotechnology. 86(4):1099-1113
- Jordan, D.B., Wagschal, K., Fan, ZM, Yuan, L., Braker, J.D. and Heng, C. 2011. Engineering lower inhibitor affinities in beta-D-xylosidase of Selenomonas ruminantium by site-directed mutagenesis of Trp145. Journal of Industrial Microbiology and Biotechnology. (in press)
- Suttipanta, N., Pattanaik, S., Kulshrestha, M., Patra, B., Singh, S.K. and Ling Yuan, 2011. The Transcription Factor CrWRKY1 Positively Regulates Terpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus. Plant Physiology. (in press) doi: 101104/pp.111.181834
- Fan, ZM and Ling Yuan. 2010. Production of Multifunctional Chimeric Enzymes in Plants: a promising Approach for Degrading Plant Cell Wall from Within. Plant Biotechnology Journal. 8:308-315
- Fan, ZM., Yuan, L., Jordan, DB., Wagschal, K., Heng, C., Braker, JD. 2010. Engineering Lower Inhibitor Affinities in Beta-D-xylosidase. Applied Microbiology and Biotechnology. 86(4):1099-1113
- Jordan, D.B., Wagschal, K., Fan, ZM, Yuan, L., Braker, J.D. and Heng, C. 2011. Engineering lower inhibitor affinities in beta-D-xylosidase of Selenomonas ruminantium by site-directed mutagenesis of Trp145. Journal of Industrial Microbiology and Biotechnology. (in press)
- Suttipanta, N., Pattanaik, S., Kulshrestha, M., Patra, B., Singh, S.K. and Ling Yuan, 2011. The Transcription Factor CrWRKY1 Positively Regulates Terpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus. Plant Physiology. (in press) doi: 101104/pp.111.181834
- Fan, ZM and Ling Yuan. 2010. Production of Multifunctional Chimeric Enzymes in Plants: a promising Approach for Degrading Plant Cell Wall from Within. Plant Biotechnology Journal. 8:308-315
- Fan, ZM., Yuan, L., Jordan, DB., Wagschal, K., Heng, C., Braker, JD. 2010. Engineering Lower Inhibitor Affinities in Beta-D-xylosidase. Applied Microbiology and Biotechnology. 86(4):1099-1113
- Jordan, D.B., Wagschal, K., Fan, ZM, Yuan, L., Braker, J.D. and Heng, C. 2011. Engineering lower inhibitor affinities in beta-D-xylosidase of Selenomonas ruminantium by site-directed mutagenesis of Trp145. Journal of Industrial Microbiology and Biotechnology. (in press)
- Suttipanta, N., Pattanaik, S., Kulshrestha, M., Patra, B., Singh, S.K. and Ling Yuan, 2011. The Transcription Factor CrWRKY1 Positively Regulates Terpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus. Plant Physiology. (in press) doi: 101104/pp.111.181834
- Fan, ZM and Ling Yuan. 2010. Production of Multifunctional Chimeric Enzymes in Plants: a promising Approach for Degrading Plant Cell Wall from Within. Plant Biotechnology Journal. 8:308-315
- Fan, ZM., Yuan, L., Jordan, DB., Wagschal, K., Heng, C., Braker, JD. 2010. Engineering Lower Inhibitor Affinities in Beta-D-xylosidase. Applied Microbiology and Biotechnology. 86(4):1099-1113
- Jordan, D.B., Wagschal, K., Fan, ZM, Yuan, L., Braker, J.D. and Heng, C. 2011. Engineering lower inhibitor affinities in beta-D-xylosidase of Selenomonas ruminantium by site-directed mutagenesis of Trp145. Journal of Industrial Microbiology and Biotechnology. (in press)
- Suttipanta, N., Pattanaik, S., Kulshrestha, M., Patra, B., Singh, S.K. and Ling Yuan, 2011. The Transcription Factor CrWRKY1 Positively Regulates Terpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus. Plant Physiology. (in press) doi: 101104/pp.111.181834
- Fan, ZM and Ling Yuan. 2010. Production of Multifunctional Chimeric Enzymes in Plants: a promising Approach for Degrading Plant Cell Wall from Within. Plant Biotechnology Journal. 8:308-315
- Fan, ZM., Yuan, L., Jordan, DB., Wagschal, K., Heng, C., Braker, JD. 2010. Engineering Lower Inhibitor Affinities in Beta-D-xylosidase. Applied Microbiology and Biotechnology. 86(4):1099-1113
- Jordan, D.B., Wagschal, K., Fan, ZM, Yuan, L., Braker, J.D. and Heng, C. 2011. Engineering lower inhibitor affinities in beta-D-xylosidase of Selenomonas ruminantium by site-directed mutagenesis of Trp145. Journal of Industrial Microbiology and Biotechnology. (in press)
- Suttipanta, N., Pattanaik, S., Kulshrestha, M., Patra, B., Singh, S.K. and Ling Yuan, 2011. The Transcription Factor CrWRKY1 Positively Regulates Terpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus. Plant Physiology. (in press) doi: 101104/pp.111.181834
- Fan, ZM and Ling Yuan. 2010. Production of Multifunctional Chimeric Enzymes in Plants: a promising Approach for Degrading Plant Cell Wall from Within. Plant Biotechnology Journal. 8:308-315
- Fan, ZM., Yuan, L., Jordan, DB., Wagschal, K., Heng, C., Braker, JD. 2010. Engineering Lower Inhibitor Affinities in Beta-D-xylosidase. Applied Microbiology and Biotechnology. 86(4):1099-1113
Lab Member
My research interests are focused in two areas. One is the engineering and mechanistic study of transcription factors (TF) for regulation of plant metabolic pathways. Long term goals include the creation of Master Transcription Factors (MTF) capable of controlling an entire metabolic pathway. Recent achievements in my laboratory not only demonstrate the feasibility of the MTF approach, but also shed light on synergistic effects between functional domains of TF on transactivation. We also verify the novel function of the engineered TFs using technology tools such as RNAi and transgenic plants. In addition, I am interested in protein- and metabolic-engineering for the improvement of bioenergy production. My laboratory applies directed enzyme evolution technologies to enhance the performance of hydrolases for biomass conversion and to modify the substrate specificities of these enzymes. Additional research efforts include the redirection of microbial metabolic pathways for the improvement of hydrogen production. My current research is supported by the US Department of Agriculture, the Department of Energy, The Kentucky Office of Energy Policy and Kentucky Tobacco Research and Development Center, University of Kentucky.
Research
My research interests are focused in two areas. One is the engineering and mechanistic study of transcription factors (TF) for regulation of plant metabolic pathways. Long term goals include the creation of Master Transcription Factors (MTF) capable of controlling an entire metabolic pathway. Recent achievements in my laboratory not only demonstrate the feasibility of the MTF approach, but also shed light on synergistic effects between functional domains of TF on transactivation. We also verify the novel function of the engineered TFs using technology tools such as RNAi and transgenic plants. In addition, I am interested in protein- and metabolic-engineering for the improvement of bioenergy production. My laboratory applies directed enzyme evolution technologies to enhance the performance of hydrolases for biomass conversion and to modify the substrate specificities of these enzymes. Additional research efforts include the redirection of microbial metabolic pathways for the improvement of hydrogen production. My current research is supported by the US Department of Agriculture, the Department of Energy, The Kentucky Office of Energy Policy and Kentucky Tobacco Research and Development Center, University of Kentucky.
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